Biogenic crystal structure determination with 3D ED.
How 3D electron diffraction solved guanine directly from crude biological material – spider integument, fish scales and scallop eyes.
What you'll learn
- How 3D ED determines structures from complex, beam-sensitive biogenic material
- How guanine was solved without isolation or growing large single crystals
- Why ED opens up naturally occurring crystals that resist conventional analysis
Why it matters
Biogenic crystals – found in spider integument, fish scales and scallop eyes – play fundamental biological roles, but their complexity and beam-sensitivity make them notoriously hard to characterise. This note shows how 3D ED determined the structure of guanine directly from crude biological material, with no isolation or large single crystals required.
At a glance: 3D ED / MicroED · guanine (biogenic) · crude biological material · no isolation needed · structures beyond conventional analysis.
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ELDICO Scientific AG, "The Electron Diffraction Company," stands at the forefront of Swiss technology and innovation. Established in 2019, ELDICO is dedicated to advancing scientific exploration with its groundbreaking electron diffractometer. This pioneering device empowers researchers to unravel the mysteries of the nanoscale world, providing precise answers to their inquiries. Through the development, production, and sale of this cutting-edge technology, ELDICO is shaping the future of particle analysis and driving progress in scientific discovery.
In 2022, ELDICO Scientific opened its Experience Centre for electron diffraction in Basel, Switzerland, showcasing its cutting-edge device, the ELDICO ED-1. Nestled within the Switzerland Innovation Park Basel, this center provides an exclusive platform for customers to delve into the world of electron diffraction. Here, they can access a range of services, including contract research, scientific application development, collaborative opportunities, and tailored training workshops. Our clientele primarily comprises researchers from industrial and R&D-intensive sectors, particularly in burgeoning fields such as pharmaceuticals, energy storage, and advanced materials.