Enhanced polymorph screening using electron diffraction.
Solid-form identification and quantification – an Ardena & ELDICO study on aripiprazole.
What you'll learn
- How 3D ED identifies the solid forms present in a screening sample
- How ED quantifies how much of each form is present
- Why early, complete solid-form knowledge de-risks development
Why it matters
Polymorph screening identifies the crystalline forms a drug can adopt – forms that govern solubility, dissolution, stability and bioavailability. In this Ardena & ELDICO study, electron diffraction both identified and quantified the solid forms of aripiprazole, adding resolution that complements conventional screening.
At a glance: 3D ED / MicroED · aripiprazole · polymorph screening · solid-form ID & quantification · an Ardena & ELDICO study.
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ELDICO Scientific AG, "The Electron Diffraction Company," stands at the forefront of Swiss technology and innovation. Established in 2019, ELDICO is dedicated to advancing scientific exploration with its groundbreaking electron diffractometer. This pioneering device empowers researchers to unravel the mysteries of the nanoscale world, providing precise answers to their inquiries. Through the development, production, and sale of this cutting-edge technology, ELDICO is shaping the future of particle analysis and driving progress in scientific discovery.
In 2022, ELDICO Scientific opened its Experience Centre for electron diffraction in Basel, Switzerland, showcasing its cutting-edge device, the ELDICO ED-1. Nestled within the Switzerland Innovation Park Basel, this center provides an exclusive platform for customers to delve into the world of electron diffraction. Here, they can access a range of services, including contract research, scientific application development, collaborative opportunities, and tailored training workshops. Our clientele primarily comprises researchers from industrial and R&D-intensive sectors, particularly in burgeoning fields such as pharmaceuticals, energy storage, and advanced materials.