Precision in powder analysis.
How electron diffraction detects residual crystallinity in milled carvedilol that PXRD can miss.
What you'll learn
- How milling can leave residual crystallinity that's hard to detect
- How 3D ED / microED resolves crystallinity below PXRD's reach
- Why detecting it matters for solubility, bioavailability and stability
Why it matters
Milling improves solubility and bioavailability but can leave residual crystallinity that powder X-ray diffraction struggles to detect. This note shows how electron diffraction (3D ED / microED) detects and characterises the residual crystallinity in milled carvedilol that conventional powder methods can miss.
At a glance: 3D ED / MicroED · carvedilol · milled pharmaceutical · residual crystallinity below PXRD's reach · solubility & stability.
Book a meeting with our team →Download the application note
After submitting the form, you'll receive an email with a link to download the application note (PDF).
ELDICO Scientific AG, "The Electron Diffraction Company," stands at the forefront of Swiss technology and innovation. Established in 2019, ELDICO is dedicated to advancing scientific exploration with its groundbreaking electron diffractometer. This pioneering device empowers researchers to unravel the mysteries of the nanoscale world, providing precise answers to their inquiries. Through the development, production, and sale of this cutting-edge technology, ELDICO is shaping the future of particle analysis and driving progress in scientific discovery.
In 2022, ELDICO Scientific opened its Experience Centre for electron diffraction in Basel, Switzerland, showcasing its cutting-edge device, the ELDICO ED-1. Nestled within the Switzerland Innovation Park Basel, this center provides an exclusive platform for customers to delve into the world of electron diffraction. Here, they can access a range of services, including contract research, scientific application development, collaborative opportunities, and tailored training workshops. Our clientele primarily comprises researchers from industrial and R&D-intensive sectors, particularly in burgeoning fields such as pharmaceuticals, energy storage, and advanced materials.