Application Note 16 – 3D ED analysis of agrochemical nanocrystals

3D ED analysis of agrochemical nanocrystals.

From spray-droplet crystallisation – a Syngenta & ELDICO study on mesotrione.

What you'll learn

  • How the solid form after spray-droplet evaporation drives bioefficacy
  • How ED crystal mapping resolves nanocrystalline material mixed with formulation
  • Why solid-form insight matters for agrochemical formulation

Why it matters

Agrochemicals are typically sprayed as diluted formulations, and the solid form left after spray droplets evaporate drives bioefficacy – yet it is nanocrystalline and mixed with other formulation components, which defeats conventional analysis. This note shows how electron diffraction crystal mapping resolves the solid form of mesotrione under these conditions.

At a glance: 3D ED / MicroED · mesotrione (agrochemical) · spray-droplet crystallisation · nanocrystalline mixtures mapped · a Syngenta & ELDICO study.

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ELDICO Scientific AG, "The Electron Diffraction Company," stands at the forefront of Swiss technology and innovation. Established in 2019, ELDICO is dedicated to advancing scientific exploration with its groundbreaking electron diffractometer. This pioneering device empowers researchers to unravel the mysteries of the nanoscale world, providing precise answers to their inquiries. Through the development, production, and sale of this cutting-edge technology, ELDICO is shaping the future of particle analysis and driving progress in scientific discovery.

In 2022, ELDICO Scientific opened its Experience Centre for electron diffraction in Basel, Switzerland, showcasing its cutting-edge device, the ELDICO ED-1. Nestled within the Switzerland Innovation Park Basel, this center provides an exclusive platform for customers to delve into the world of electron diffraction. Here, they can access a range of services, including contract research, scientific application development, collaborative opportunities, and tailored training workshops. Our clientele primarily comprises researchers from industrial and R&D-intensive sectors, particularly in burgeoning fields such as pharmaceuticals, energy storage, and advanced materials.